CP-226,269

In this article we are going to address the topic of CP-226,269 from different perspectives with the aim of providing a broad and complete vision of this matter. Along these lines we will explore the different facets of CP-226,269, analyzing its impact in various areas and offering a deep reflection on its meaning and relevance in the current context. From its origin to its evolution, through its influence on society and its relationship with other relevant topics, this article seeks to contribute to the knowledge and understanding of CP-226,269 in a comprehensive and enriching way.

CP-226,269
Identifiers
  • 5-fluoro-2--1H-indole
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H19FN4
Molar mass310.376 g·mol−1
3D model (JSmol)
  • n4ccccc4N3CCN(CC3)Cc2cc1cc(F)ccc12
  • InChI=1S/C18H19FN4/c19-15-4-5-17-14(11-15)12-16(21-17)13-22-7-9-23(10-8-22)18-3-1-2-6-20-18/h1-6,11-12,21H,7-10,13H2 checkY
  • Key:PQOIDBZLMJMYCD-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

CP-226,269 is a drug which acts as a dopamine agonist selective for the D4 subtype, which is used for researching the role of D4 receptors in the brain.[1][2]

References

  1. ^ Sharma A, Kramer ML, Wick PF, Liu D, Chari S, Shim S, Tan W, Ouellette D, Nagata M, DuRand CJ, Kotb M, Deth RC (May 1999). "D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia". Molecular Psychiatry. 4 (3): 235–46. doi:10.1038/sj.mp.4000522. PMID 10395213.
  2. ^ Basso AM, Gallagher KB, Bratcher NA, Brioni JD, Moreland RB, Hsieh GC, Drescher K, Fox GB, Decker MW, Rueter LE (July 2005). "Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test". Neuropsychopharmacology. 30 (7): 1257–68. doi:10.1038/sj.npp.1300677. PMID 15688083.
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