Amedalin

In today's world, Amedalin has become a topic of great relevance and interest to a wide spectrum of people. Whether due to its impact on society, its historical relevance or its influence in different areas, Amedalin has captured the attention and curiosity of individuals of all ages and professions. Over the years, Amedalin has been the subject of debate, analysis and study, generating a large amount of information and opinions about it. In this article, we will explore the different aspects, perspectives and possible implications of Amedalin, addressing its importance from various perspectives and offering a comprehensive view of the topic.

Amedalin
Clinical data
ATC code
  • None
Identifiers
  • 3-Methyl-3--1-phenyl-1,3-dihydro-2H-indol-2-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H22N2O
Molar mass294.398 g·mol−1
3D model (JSmol)
  • CC1(C2=CC=CC=C2N(C1=O)C3=CC=CC=C3)CCCNC
  • InChI=1S/C19H22N2O/c1-19(13-8-14-20-2)16-11-6-7-12-17(16)21(18(19)22)15-9-4-3-5-10-15/h3-7,9-12,20H,8,13-14H2,1-2H3 checkY
  • Key:HBGWAZBZXJBYQD-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Amedalin (UK-3540-1) is an antidepressant which was synthesized in the early 1970s but was never marketed.[1][2] It is a selective norepinephrine reuptake inhibitor, with no significant effects on the reuptake of serotonin and dopamine, and no antihistamine or anticholinergic properties.[2][3]

See also

References

  1. ^ Triggle DJ (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 978-0-412-46630-4.
  2. ^ a b Cañas-Rodriguez A, Leeming PR (July 1972). "N-Phenyl-2-indolinones and N-phenylindolines. A new class of antidepressant agents". Journal of Medicinal Chemistry. 15 (7): 762–70. doi:10.1021/jm00277a017. PMID 5043876.
  3. ^ Koe BK (December 1976). "Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain". Journal of Pharmacology and Experimental Therapeutics. 199 (3): 649–661. PMID 994022.
Stub icon

This article about an amine is a stub. You can help Wikipedia by expanding it.

Stub icon

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

Wikious
Boobota
Sagapedia