In today's world, 3C-BZ is a topic that has gained unprecedented relevance. With the advancement of technology and globalization, 3C-BZ has become a point of interest for people of all ages and walks of life. From its impact on society to its implications in popular culture, 3C-BZ is a topic that leaves no one indifferent. In this article, we will explore different aspects related to 3C-BZ, from its origin to its possible future developments. Let yourself be carried away by this journey and discover how 3C-BZ has marked a before and after in the world we live in.
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Names | |
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Preferred IUPAC name
1-propan-2-amine | |
Other names
4-Benzyloxy-3,5-methoxyamphetamine
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider |
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PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C18H23NO3 | |
Molar mass | 301.386 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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3C-BZ (4-benzyloxy-3,5-dimethoxyamphetamine) is a lesser-known psychedelic drug and a substituted amphetamine. 3C-BZ was first synthesized by Alexander Shulgin. In his book PiHKAL, the dosage range is listed as 25–200 mg and the duration as 18–24 hours. According to anecdotal reports from the substance's entry in PiHKAL, 3C-BZ's effects can vary significantly, ranging from intensified emotions and strange dreams, to effects similar to those of LSD or TMA. Very little data exists about the pharmacological properties, metabolism, and toxicity of 3C-BZ.
3C-BZ was originally synthesized by Alexander Shulgin starting from 5-methoxyeugenol (4-allyl-2,6-dimethoxyphenol) through a reaction with benzyl chloride to form the benzyloxy derivative of 5-methoxyeugenol. The obtained benzyl derivative was reacted with tetranitromethane to form 1--2-nitro-1-propene, from which 3C-BZ is obtained by reduction of the nitropropene with lithium aluminium hydride.
Another possible synthetic route would be the reaction of benzyl chloride with syringaldehyde to form 3,5-dimethoxy-4-benzyloxybenzaldehyde followed by condensation with nitroethane to form 1--2-nitro-1-propene. The obtained nitropropene can be reduced using lithium aluminium hydride, Red-Al, or an aluminium-mercury amalgam.
Phenethylamines |
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Amphetamines |
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Phentermines |
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Cathinones |
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Phenylisobutylamines | |
Phenylalkylpyrrolidines | |
Catecholamines (and close relatives) |
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Miscellaneous |
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Psychedelics (5-HT2A agonists) |
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Dissociatives (NMDAR antagonists) |
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Deliriants (mAChR antagonists) |
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Others |
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