Triclonide

In today's article we are going to talk about Triclonide, a topic that undoubtedly generates interest and curiosity in many people. Triclonide is a topic that has been the subject of debate and study over the years, awakening conflicting opinions and generating a great impact on society. From its origins to the present, Triclonide has played an important role in different areas, influencing the way we think, act and relate to the world around us. Throughout this article, we will explore different aspects of Triclonide, analyze its implications and discuss its relevance today. Get ready to immerse yourself in the fascinating world of Triclonide!

Triclonide
Clinical data
Other namesRS-4464; 6α-Fluoro-9α,11β,21-trichloro-16α,17α-dihydroxypregna-1,4-diene-3,20-dione cyclic acetal with acetone; 6α-Fluoro-9α,11β,21-trichloro-16α,17α-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,5-Dichloro-6b-(chloroacetyl)-12-fluoro-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphthoindenodioxol-2-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC24H28Cl3FO4
Molar mass505.83 g·mol−1
3D model (JSmol)
  • C12C(3((1C42(OC(O4)(C)C)C(=O)CCl)C(C5=CC(=O)C=C53C)F)Cl)Cl
  • InChI=1S/C24H28Cl3FO4/c1-20(2)31-19-9-13-14-8-16(28)15-7-12(29)5-6-21(15,3)23(14,27)17(26)10-22(13,4)24(19,32-20)18(30)11-25/h5-7,13-14,16-17,19H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
  • Key:VSVSLEMVVAYTQW-VSXGLTOVSA-N

Triclonide (developmental code name RS-4464) is a synthetic glucocorticoid corticosteroid which was never marketed.

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 282, 486. ISBN 978-1-4757-2085-3.
  2. ^ Challener CA (1 December 2001). Chiral Drugs. Wiley. p. 312. ISBN 978-0-566-08411-9.