Oxypertine

In today's world, Oxypertine is a topic that has gained great relevance and has aroused widespread interest in society. Whether due to its impact on people's daily lives, its relevance in the professional field or its influence on technological development, Oxypertine has become a recurring topic of conversation in different areas. In this article, we will thoroughly explore the most relevant aspects of Oxypertine and analyze its importance in the current context. Additionally, we will examine its evolution over time and its possible impact in the future.

Oxypertine
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
By mouth
ATC code
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)[1]
  • In general: ℞ (Prescription only)
Identifiers
  • 5,6-Dimethoxy-2-methyl-3--1H-indole
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.005.291 Edit this at Wikidata
Chemical and physical data
FormulaC23H29N3O2
Molar mass379.504 g·mol−1
3D model (JSmol)
  • CC1=C(C2=CC(=C(C=C2N1)OC)OC)CCN3CCN(CC3)C4=CC=CC=C4
  • InChI=1S/C23H29N3O2/c1-17-19(20-15-22(27-2)23(28-3)16-21(20)24-17)9-10-25-11-13-26(14-12-25)18-7-5-4-6-8-18/h4-8,15-16,24H,9-14H2,1-3H3 ☒N
  • Key:XCWPUUGSGHNIDZ-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Oxypertine (Equipertine, Forit, Integrin, Lanturil, Lotawin, Opertil) is an antipsychotic used in the treatment of schizophrenia.[2] It was also evaluated for the treatment of anxiety at a dosage of 20 mg per day.[3] Chemically, it is an indole and phenylpiperazine derivative.[4] Like reserpine and tetrabenazine, oxypertine depletes catecholamines, though not serotonin, possibly underlying its neuroleptic efficacy.[5] Its structure is similar to solypertine and milipertine.

See also

References

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. ^ Hall C, Rhodes PH (1996). Dictionary of organic compounds. London: Chapman & Hall. ISBN 0-412-54090-8.
  3. ^ Somohano MD, Broissin MC, Sobrino ZA (1976). "". Neurologia, Neurocirugia, Psiquiatria (in Spanish). 17 (3): 171–180. PMID 12484.
  4. ^ Breulet M, Labar P, Delree C, Collard J, Bobon J (February 1968). "". Acta Neurologica et Psychiatrica Belgica (in French). 68 (2): 116–127. PMID 4972600.
  5. ^ Bak IJ, Hassler R, Kim JS (1969). "Differential monoamine depletion by oxypertine in nerve terminals. Granulated synaptic vesicles in relation to depletion of norepinephrine, dopamine and serotonin". Zeitschrift für Zellforschung und Mikroskopische Anatomie. 101 (3): 448–462. doi:10.1007/BF00335580. PMID 5362847. S2CID 32583722.